NFL look ahead lines for week 11 are posted by Betonline, home of the opening line. All the best picks on these games will be at OffshoreInsiders.com
| New Orleans Saints | -5½ | -120 | 51 | -110 |
| Tampa Bay Buccaneers | +5½ | 100 | 51 | -110 |
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| Atlanta Falcons | +6½ | -108 | 53 | 105 |
| Carolina Panthers | -6½ | -112 | 53 | -125 |
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| Denver Broncos | 10 | -110 | 38½ | -110 |
| Minnesota Vikings | -10 | -110 | 38½ | -110 |
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| New York Jets | +1½ | -105 | 37½ | -110 |
| Washington Redskins | -1½ | -115 | 37½ | -110 |
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| Buffalo Bills | -7½ | -105 | 39 | -110 |
| Miami Dolphins | +7½ | -115 | 39 | -110 |
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| Houston Texans | 4 | -110 | 49 | -110 |
| Baltimore Ravens | -4 | -110 | 49 | -110 |
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| Arizona Cardinals | +13½ | -110 | 44½ | -115 |
| San Francisco 49ers | -13½ | -110 | 44½ | -105 |
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| New England Patriots | -3 | -125 | 46 | -105 |
| Philadelphia Eagles | 3 | 105 | 46 | -115 |
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| Cincinnati Bengals | +8½ | -110 | 48 | -110 |
| Oakland Raiders | -8½ | -110 | 48 | -110 |
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| Chicago Bears | 7 | 105 | 42 | -110 |
| Los Angeles Rams | -7 | -125 | 42 | -110 |
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| Kansas City Chiefs | -4 | 100 | 49 | -110 |
| Los Angeles Chargers | 4 | -120 | 49 | -110 |