The Broncos vs. 49ers point spread is San Francisco -2 with a total of 42. The game is played in London, England.

The world’s paramount sports handicappers achieve the utmost scrutinizing the subsequent key performance indicators in foreseeing the point spread picks with the performance gap breakdowns.

Differentiating the yards per rush records on offense, the specifics assign the plus row to San Francisco by 1.3.

Grading passing yards per catch on offense, the totaling supports the Denver Broncos by 1.5.

Countless sportsbook whales capitalize on yards per point. Offensively the most desirable final tallies are owned by the Broncos by 2.2.

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Defensively the more effective troop against the run documented by yards per rush is the 49ers by .5.

Yards per reception numerals make higher the defense of San Francisco by 1.3.

Sums on the yards per point arithmetic give the benefit in the checkbox of Denver by 1.0.

Onward to net turnover margin, the more capable squad is Denver by nine.

Yards per point is determined by diving total yards by number of points. Offensively a lower number is considered more efficient. On defense, a higher number is better.